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levofloxacine

J - Antiinfectives For Systemic Use -> J01 - Antibacterials For Systemic Use -> J01M - Quinolone Antibacterials -> J01MA - Fluoroquinolones -> J01MA12 - Levofloxacin
Administration category: Free Medicine group: antibacterial Brand name: Tavanic

Safety margins

≥ 18 years
Weight ROA Dosage
ROA:
po
Dosage:
min. 250mg 1 dd to max. 500mg 2 dd
ROA:
iv
Dosage:
min. 250mg 1 dd to max. 500mg 2 dd

Kidney function

≥ 18 years
ROA GFR Dosage Interval Comments
ROA: iv
GFR:
30 - 50
Dosage:
50%
GFR:
10 - 30
Dosage:
25%
ROA: po
GFR:
30 - 50
Dosage:
50%
GFR:
10 - 30
Dosage:
25%
Renal elimination: 93%
Dosage: dependent on kidney function

Renal function-replacement therapy

CAPD: Normale startdosis, vervolgens 25% van de normale keerdosis bij gelijkblijvend doseringsinterval.

Hemo dialysis: Normale startdosis, vervolgens 25% van de normale keerdosis bij gelijkblijvend doseringsinterval.

CAV / VVHD: Normale startdosis, vervolgens 25% van de normale keerdosis bij gelijkblijvend doseringsinterval.

Interactions

Interaction with (ATC): Interaction with: Expected effect:
Interaction with (ATC):
Interaction with:
aluminium- en magnesiumzouten bevattende antacida
Expected effect:
vermindering absorptie levofloxacine
Interaction with (ATC):
Interaction with:
ijzerzouten
Expected effect:
vermindering absorptie levofloxacine
Interaction with (ATC):
R03DA04 - Theophylline
Interaction with:
Expected effect:
verhoging plasmaconcentratie theofylline

Pregnancy

Due to the expiration of the alphanumeric classification for use in pregnancy and lactation, reference is made to the current, online information of the Teratology Information Service (TIS) of LAREB:

For individual advice, consult an expert on site.
Metadata

Swab vid: M-1520.2
Updated: 06/16/2019 - 20:05
Status: Published

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