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imipenem + cilastine

J - Antiinfectives For Systemic Use -> J01 - Antibacterials For Systemic Use -> J01D - Other Beta-Lactam Antibacterials -> J01DH - Carbapenems -> J01DH51 - Imipenem And Enzyme Inhibitor
Administration category: Free Medicine group: antibacterial Brand name: Tienam

Safety margins

≥ 18 years
Weight ROA Dosage
ROA:
iv
Dosage:
min. 250mg 4 dd to max. 1000mg 4 dd
Comments:

dosisadvies heeft betrekking op imipenem component

Kidney function

≥ 18 years
ROA GFR Dosage Interval Comments
ROA: iv
GFR:
10 - 30
Dosage:
50%
Renal elimination: 70%
Dosage: dependent on kidney function

Renal function-replacement therapy

CAPD: 500 mg elke 12 uur, max. 1000 mg per dag

Hemo dialysis: 500 mg elke 12 uur, max. 1000 mg per dag, op dialysedagen 1 dosis na de dialyse

CAV / VVHD: 500 mg elke 12 uur, max. 1000 mg per dag

Pregnancy

Due to the expiration of the alphanumeric classification for use in pregnancy and lactation, reference is made to the current, online information of the Teratology Information Service (TIS) of LAREB:

For individual advice, consult an expert on site.
Metadata

Swab vid: M-1495.4
Updated: 06/16/2019 - 20:05
Status: Published

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